Prophylactic ethamsylate for periventricular haemorrhage.

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Prophylactic ethamsylate for periventricular haemorrhage.

Drs Cooke and Morgan have shown in a double blind trial that ethamsylate seemed to reduce the incidence of periventricular haemorrhage.' Although this is of great interest, no confirmation of these results is available so far. Yet Delandale Laboratories are already advertising ethamsylate as the drug to prevent periventricular haemorrhage in the newborn infant. In the past similar effects, clai...

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Prophylactic ethamsylate for periventricular haemorrhage.

Drug prophylaxis with ethamsylate for periventricular haemorrhage in very low birthweight infants significantly reduced the incidence of periventricular haemorrhage in survivors. A reduction in abnormalities at follow up and in insertion of ventriculoperitoneal shunts was also noted.

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Reduction in periventricular haemorrhage in preterm infants.

Our previous cerebral ultrasound study of antecedents of periventricular haemorrhage in infants weighing 1250 g or less at birth suggested that neonatal events that caused increased or fluctuating cerebral blood flow lead to periventricular haemorrhage. As the risk period for this type of haemorrhage was the first four days of life strict guidelines were introduced to avoid the previously ident...

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Timing and evolution of periventricular haemorrhage

on serial scans. The median age was 16 hours when PVH was first detected and 48 hours when PVH reached its maximum extent. Ventricular size at birth correlated with gestation. Progressive ventricular growth was seen after birth in infants both with and without PVH. Charts of normal ranges of ventricular size and head circumference were drawn up from birth to 10 weeks of age. All infants with PV...

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Tranexamic acid in the prevention of periventricular haemorrhage.

Increased fibrinolytic activity in the ganglionic eminence of the preterm human brain has been proposed as a factor in the aetiology of periventricular haemorrhage. The effect of tranexamic acid in preventing periventricular haemorrhage was evaluated in 100 infants in a double blind, randomised controlled trial. Haemorrhages developed in 22 infants who received tranexamic acid and in 20 of thos...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1984

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.59.5.489